Journal article
Neutralisation of SARS-CoV-2 lineage P.1 by antibodies elicited through natural SARS-CoV-2 infection or vaccination with an inactivated SARS-CoV-2 vaccine: an immunological study
- Abstract:
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Background
Mutations accrued by SARS-CoV-2 lineage P.1—first detected in Brazil in early January, 2021—include amino acid changes in the receptor-binding domain of the viral spike protein that also are reported in other variants of concern, including B.1.1.7 and B.1.351. We aimed to investigate whether isolates of wild-type P.1 lineage SARS-CoV-2 can escape from neutralising antibodies generated by a polyclonal immune response.
Methods
We d... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 2.1MB, Terms of use)
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- Publisher copy:
- 10.1016/s2666-5247(21)00129-4
Authors
- Publisher:
- Elsevier
- Journal:
- The Lancet Microbe More from this journal
- Volume:
- 2
- Issue:
- 10
- Pages:
- E527-E535
- Publication date:
- 2021-07-08
- Acceptance date:
- 2021-05-19
- DOI:
- EISSN:
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2666-5247
- Language:
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English
- Keywords:
- Pubs id:
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1186867
- Local pid:
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pubs:1186867
- Deposit date:
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2021-07-18
- ARK identifier:
Terms of use
- Copyright holder:
- Souza et al
- Copyright date:
- 2021
- Rights statement:
- ©2021 The Author(s). Published by Elsevier Ltd. This article is available under the Creative Commons CC-BY-NC-ND license and permits non-commercial use of the work as published, without adaptation or alteration provided the work is fully attributed.
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