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High confidence prediction of essential genes in Burkholderia cenocepacia

Abstract:

Background Essential genes are absolutely required for the survival of an organism. The identification of essential genes, besides being one of the most fundamental questions in biology, is also of interest for the emerging science of synthetic biology and for the development of novel antimicrobials. New antimicrobial therapies are desperately needed to treat multidrug-resistant pathogens, such as members of the Burkholderia cepacia complex. Methodology/Principal Findings We hypothesize that ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0040064

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Role:
Author
Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
7
Issue:
6
Pages:
ARTN e40064
Publication date:
2012-06-29
Acceptance date:
2012-05-31
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Language:
English
Keywords:
UUID:
uuid:295bc80b-9e56-405e-bb28-54d5986b0622
Local pid:
pubs:342942
Source identifiers:
342942
Deposit date:
2013-11-16

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