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Cell interactions in the immune response in vitro. 3. Specific collaboration across a cell impermeable membrane.

Abstract:

Tissue cultures with two compartments, separated by a cell impermeable nuclepore membrane (1 micro pore size), were used to investigate the mechanism of T-B lymphocyte cooperation. It was found that collaboration was as effective when the T and B lymphocyte populations were separated by the membrane as when they were mixed together. Critical tests were performed to verify that the membranes used were in fact cell impermeable. The specificity of the augmentation of the B cell response by vario...

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Publisher copy:
10.1084/jem.136.1.49

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
The Journal of experimental medicine
Volume:
136
Issue:
1
Pages:
49-67
Publication date:
1972-07-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:28cf3811-1649-4245-b82f-24d5c6794cc8
Source identifiers:
482223
Local pid:
pubs:482223

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