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Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy.

Abstract:

Due to their rapid and highly selective nature, bioorthogonal chemistry reactions are attracting a significant amount of recent interest in the radiopharmaceutical community. Over the last few years, reactions of this type have found tremendous utility in the construction of new radiopharmaceuticals and as a method of bioconjugation. Furthermore, reports are beginning to emerge in which these reactions are also being applied in vivo to facilitate a novel pretargeting strategy for the imaging ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
Cancer Research UK More from this funder
Publisher:
e-Century Publishing Publisher's website
Journal:
American journal of nuclear medicine and molecular imaging Journal website
Volume:
4
Issue:
2
Pages:
96-113
Publication date:
2014-01-01
EISSN:
2160-8407
URN:
uuid:28cea8ed-3108-4032-8651-a483830dfbc1
Source identifiers:
462854
Local pid:
pubs:462854

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