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Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature

Abstract:
Background
Appropriate treatment and management of children presenting with fever depend on accurate and timely diagnosis, but current diagnostic tests lack sensitivity and specificity and are frequently too slow to inform initial treatment. As an alternative to pathogen detection, host gene expression signatures in blood have shown promise in discriminating several infectious and inflammatory diseases in a dichotomous manner. However, differential diagnosis requires simu... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.medj.2023.06.007

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Name:
European Commission
Grant:
279185
668303
Publisher:
Cell Press
Journal:
Med More from this journal
Volume:
4
Issue:
9
Pages:
P635-654.E5
Place of publication:
United States
Publication date:
2023-08-11
Acceptance date:
2023-06-19
DOI:
EISSN:
2666-6340
ISSN:
2666-6359
Pmid:
37597512
Language:
English
Keywords:
Pubs id:
1514637
Local pid:
pubs:1514637
Deposit date:
2023-09-19

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