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Associations between arterial stiffening and brain structure, perfusion and cognition in the Whitehall II Imaging Sub-study: a retrospective cohort study

Abstract:

Background: Aortic stiffness is closely linked with cardiovascular diseases, but recent studies suggest that it is also a risk factor for cognitive decline and dementia. However, the brain changes underlying this risk are unclear. We examined whether aortic stiffening during a 4-year follow-up in mid to late-life was associated with brain structure and cognition in the Whitehall II Imaging Sub-study.
Methods and Findings: The Whitehall II Imaging coh... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.1003467

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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Medicine Journal website
Volume:
17
Issue:
12
Article number:
e1003467
Publication date:
2020-12-29
Acceptance date:
2020-11-13
DOI:
ISSN:
1549-1277
Language:
English
Keywords:
Pubs id:
1140131
Local pid:
pubs:1140131
Deposit date:
2020-11-13

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