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The ratio of monocytes to lymphocytes in peripheral blood correlates with increased susceptibility to clinical malaria in Kenyan children.

Abstract:

BACKGROUND: Plasmodium falciparum malaria remains a major cause of illness and death in sub-Saharan Africa. Young children bear the brunt of the disease and though older children and adults suffer relatively fewer clinical attacks, they remain susceptible to asymptomatic P. falciparum infection. A better understanding of the host factors associated with immunity to clinical malaria and the ability to sustain asymptomatic P. falciparum infection will aid the development of improved strategies ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0057320

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Murungi, LM More by this author
Nyangweso, GM More by this author
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Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
8
Issue:
2
Pages:
e57320
Publication date:
2013
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:27ba9709-d5fa-4ba1-b95b-974dd5e881e8
Source identifiers:
387004
Local pid:
pubs:387004

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