Journal article icon

Journal article

Virologic response to first-line efavirenz- or nevirapine-based anti-retroviral therapy in HIV-infected African children

Abstract:

Background

Poorer virologic response to nevirapine vs efavirenz-based antiretroviral therapy (ART) has been reported in adult systematic reviews and paediatric studies.

Methods

We compared drug discontinuation and viral load (VL) response in ART-naïve Ugandan/Zimbabwean children aged ≥3 years initiating ART with clinician-chosen nevirapine vs efavirenz in the ARROW trial. Predictors of suppression <80, <400 and <1000 copies/ml at 36, 48 and 144 weeks were...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

Actions


Access Document


Files:
Publisher copy:
10.1097/INF.0000000000001505

Authors


Expand authors...
Medical Research Council More from this funder
Department for International Development More from this funder
ViiV Healthcare/GlaxoSmithKline More from this funder
Publisher:
Lippincott, Williams and Wilkins Publisher's website
Journal:
Journal of Pediatric Infectious Diseases Journal website
Volume:
36
Issue:
6
Pages:
588–594
Publication date:
2017-06-05
Acceptance date:
2016-09-12
DOI:
ISSN:
1305-7707
Pubs id:
pubs:647880
URN:
uri:27b01aa4-7c97-4ff4-a941-ce6e05b2afb8
UUID:
uuid:27b01aa4-7c97-4ff4-a941-ce6e05b2afb8
Local pid:
pubs:647880

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP