Journal article icon

Journal article

Scaling-down antibody radiolabeling reactions with zirconium-89

Abstract:
The most widely cited procedures for radiolabeling antibodies with zirconium-89 for immuno-PET require multi-milligram amounts of antibody which can be cost-prohibitive, particularly during the research and development process. We therefore sought to develop a reliable 89Zr-radiolabeling procedure that provides high radiochemical yields at the microgram scale.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

Actions


Access Document


Publisher copy:
10.1039/C5DT04774A

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Paisey, SJ More by this author
Dabkowski, AM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Williams, AS More by this author
Expand authors...
CRUK/MRC Oxford Institute for Radiation Oncology More from this funder
CRUK/MRC Oxford Institute for Cancer Imaging More from this funder
Expand funders...
Publisher:
Royal Society of Chemistry Publisher's website
Journal:
Dalton Transactions Journal website
Volume:
45
Issue:
15
Pages:
6343-6347
Publication date:
2016
DOI:
EISSN:
1477-9234
ISSN:
1477-9226
URN:
uuid:2783b3f6-238b-43ef-b9aa-002f0395a85f
Source identifiers:
610263
Local pid:
pubs:610263

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP