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Journal article

Scaling-down antibody radiolabeling reactions with zirconium-89

Abstract:
The most widely cited procedures for radiolabeling antibodies with zirconium-89 for immuno-PET require multi-milligram amounts of antibody which can be cost-prohibitive, particularly during the research and development process. We therefore sought to develop a reliable 89Zr-radiolabeling procedure that provides high radiochemical yields at the microgram scale.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/C5DT04774A

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author


Publisher:
Royal Society of Chemistry
Journal:
Dalton Transactions More from this journal
Volume:
45
Issue:
15
Pages:
6343-6347
Publication date:
2016-03-11
Acceptance date:
2016-03-07
DOI:
EISSN:
1477-9234
ISSN:
1477-9226


Language:
English
Pubs id:
pubs:610263
UUID:
uuid:2783b3f6-238b-43ef-b9aa-002f0395a85f
Local pid:
pubs:610263
Source identifiers:
610263
Deposit date:
2016-03-16

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