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Thesis

Beta-adrenergic stimulation and cardiac arrhythmogenesis in the infarct border zone

Abstract:

Sudden cardiac death due to ventricular arrhythmias after myocardial infarction (MI) is a major cause of mortality worldwide. Following a MI, the heart undergoes considerable remodelling; however, the precise mechanisms of how the changes induce arrhythmia have not been fully elucidated. The role of sympathetic innervation in the infarct border zone (BZ) is particularly controversial: while historical evidence posits a strongly proarrhythmic role, recent clinical studies report that i...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Department:
Oxford
Role:
Author

Contributors

Department:
McGill
Role:
Supervisor
Department:
Oxford
Role:
Supervisor
Role:
Supervisor
Engineering & Physical Sciences Research Council More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:277d3767-f93b-41ef-82ae-ddb4e65117f0
Deposit date:
2018-06-14

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