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Effects of aspirin on risk and severity of early recurrent stroke after transient ischaemic attack and ischaemic stroke: time-course analysis of randomised trials

Abstract:

Background Aspirin is recommended for secondary prevention after transient ischaemic attack (TIA) or ischaemic stroke on the basis of trials showing a 13% reduction in long-term risk of recurrent stroke. However, the risk of major stroke is very high for only the first few days after TIA and minor ischaemic stroke, and observational studies show substantially greater benefits of early medical treatment in the acute phase than do longer-term trials. We hypothesised that the...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S0140-6736(16)30468-8

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
St Edmund Hall
Role:
Author
More by this author
Institution:
University of Oxford
Oxford college:
Green Templeton College
Role:
Author


Publisher:
Elsevier
Journal:
Lancet More from this journal
Volume:
388
Issue:
10042
Pages:
365-375
Publication date:
2016-05-18
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Pmid:
27209146


Language:
English
Keywords:
Pubs id:
pubs:623583
UUID:
uuid:27728b90-ec86-4d37-a949-994c099ad265
Local pid:
pubs:623583
Deposit date:
2016-12-13

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