Journal article

YACs, BACs, PACs and MACs: artificial chromosomes as research tools.

Abstract:: Yeast artificial chromosomes (YACs) have become essential research tools as they enable large fragments of DNA to be cloned. In order to overcome several disadvantages of YACs, including chimaerism and instability, several complementary bacterial artificial chromosome (BAC) vectors have been developed. More recently, attempts are being made to construct artificial chromosomes in mammalian cells (MACs).

Publication status:: Published

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APA Style

Monaco, A., & Larin, Z. (1994). YACs, BACs, PACs and MACs: artificial chromosomes as research tools. Trends in Biotechnology, 12(7), 280–286.

MLA Style

Monaco, A., and Z. Larin. “YACs, BACs, PACs and MACs: Artificial Chromosomes as Research Tools.” Trends in Biotechnology, vol. 12, no. 7, Elsevier, 1994, pp. 280–86.

Chicago Style

Monaco, A, and Z Larin. 1994. “YACs, BACs, PACs and MACs: Artificial Chromosomes as Research Tools.” Trends in Biotechnology 12 (7): 280–86.
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Publisher copy:: 10.1016/0167-7799(94)90140-6

Authors

+ Monaco, A More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Human Genetics Wt Centre
Role:: Author

+ Larin, Z More by this author

Role:: Author

Publisher:: Elsevier
Journal:: Trends in biotechnology More from this journal
Volume:: 12
Issue:: 7
Pages:: 280-286
Publication date:: 1994-07-01
DOI:: 10.1016/0167-7799(94)90140-6
EISSN:: 1879-3096
ISSN:: 0167-7799

Language:: English
Keywords:: Chromosomes, Human

Mammals

Humans

Chromosomes, Artificial, Yeast

Chromosomes, Bacterial

Genetic Vectors

Animals

Cloning, Molecular

Bacteriophage P1
Pubs id:: pubs:35695
UUID:: uuid:273c7b3b-6c1a-4025-ad94-f2479def2160
Local pid:: pubs:35695
Source identifiers:: 35695
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 1994

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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