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Journal article

Single or combined immune checkpoint inhibitors compared to first‐line platinum‐based chemotherapy with or without bevacizumab for people with advanced non‐small cell lung cancer

Abstract:

Background

Immune checkpoint inhibitors (ICIs) targeting the PD‐1/PD‐L1 axis have changed the first‐line treatment of people with advanced non‐small cell lung cancer (NSCLC). Single‐agent pembrolizumab (a PD‐1 inhibitor) is currently the standard of care as monotherapy in patients with PD‐L1 expression ≥ 50%, either alone or in combination with chemotherapy when PD‐L1 expression is less than 50%. Atezolizumab (PD‐L1 inhibitor) has also been approved in combination w...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1002/14651858.cd013257.pub2

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
NPEU
Role:
Author


Publisher:
Cochrane Collaboration
Journal:
Cochrane Database of Systematic Reviews More from this journal
Volume:
2020
Issue:
12
Article number:
CD013257
Publication date:
2020-12-14
DOI:
EISSN:
1469-493X
Pmid:
33316104


Language:
English
Keywords:
Pubs id:
1150733
Local pid:
pubs:1150733
Deposit date:
2021-06-01

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