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Maternal protein deficiency affects mesenchymal stem cell activity in the developing offspring.

Abstract:

Epidemiological studies suggest that environmental influences such as maternal nutrition, programme skeletal growth during intrauterine and early postnatal life. However, the mechanism whereby the skeletal growth trajectory is modified remains unclear. We have addressed this using a rat model of maternal protein insufficiency to investigate the cellular mechanisms involved in the programming of bone development. The aims of this study were to determine whether colony formation (colony forming...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Bone
Volume:
33
Issue:
1
Pages:
100-107
Publication date:
2003-07-05
DOI:
EISSN:
1873-2763
ISSN:
8756-3282
URN:
uuid:272644a5-e064-4134-af17-4bee7429962b
Source identifiers:
126389
Local pid:
pubs:126389

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