Journal article : Letter
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
- Abstract:
-
Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease1. We conducted a GWAS using 21,468 ER-negative cases and 100,594 controls combined with 18,908 BRCA1 mutation carriers (9,414 with breast cancer), all of European origin. We identified independent associations at P < 5 × 10−8 with ten variants at nine new loci. At P < 0.05, we replicated associations with 10 of 11 ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- Springer Nature
- Journal:
- Nature Genetics More from this journal
- Volume:
- 49
- Issue:
- 12
- Pages:
- 1767-1778
- Publication date:
- 2017-10-23
- Acceptance date:
- 2017-01-11
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- Pmid:
-
29058716
Item Description
- Language:
- English
- Keywords:
- Subtype:
- Letter
- Pubs id:
-
pubs:738471
- UUID:
-
uuid:26eac704-6ac0-4dea-837b-1f65f56d77d7
- Local pid:
- pubs:738471
- Source identifiers:
-
738471
- Deposit date:
- 2019-02-28
Terms of use
- Copyright holder:
- Nature America, Inc
- Copyright date:
- 2017
- Notes:
- © 2017 Nature America, Inc., part of Springer Nature. All rights reserved.
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