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No evidence of cardiotoxicity during antimalarial treatment with artemether-lumefantrine.

Abstract:

Artemether-lumefantrine is a new fixed antimalarial combination effective against multidrug-resistant falciparum malaria. A prospective electrocardiographic study was conducted in 150 patients receiving artemetherlumefantrine and 50 treated with artesunate-mefloquine. There was no evidence for clinically significant changes in the electrocardiographic intervals and in particular no relationship between plasma concentrations of lumefantrine and QTc prolongation. Artemether-lumefantrine does no...

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Publication status:
Published

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Journal:
The American journal of tropical medicine and hygiene
Volume:
61
Issue:
6
Pages:
964-967
Publication date:
1999-12-05
EISSN:
1476-1645
ISSN:
0002-9637
URN:
uuid:26c15b20-685a-4330-aee5-af704dbc2ead
Source identifiers:
21199
Local pid:
pubs:21199

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