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A cell cycle model for somitogenesis: mathematical formulation and numerical simulation.

Abstract:

After many years of research, the mechanisms that generate a periodic pattern of repeated elements (somites) along the length of the embryonic body axis is still one of the major unresolved problems in developmental biology. Here we present a mathematical formulation of the cell cycle model for somitogenesis proposed in Development105 (1989), 119-130. Somite precursor cells in the node are asynchronous, and therefore, as a population, generate continuously pre-somite cells which enter the seg...

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Publication status:
Published

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Publisher copy:
10.1006/jtbi.2000.2172

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
Journal:
Journal of theoretical biology
Volume:
207
Issue:
3
Pages:
305-316
Publication date:
2000-12-01
DOI:
EISSN:
1095-8541
ISSN:
0022-5193
Source identifiers:
14794
Language:
English
Keywords:
Pubs id:
pubs:14794
UUID:
uuid:268fd0ce-999f-4d28-a6b0-9a2e915d92a5
Local pid:
pubs:14794
Deposit date:
2012-12-19

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