Journal article
Identifying bacterial airways infection in stable severe asthma using Oxford nanopore sequencing technologies
- Abstract:
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Previous metagenomic studies in asthma have been limited by inadequate sequencing depth for species-level bacterial identification and by heterogeneity in clinical phenotyping. We hypothesize that chronic bacterial airways infection is a key “treatable trait” whose prevalence, clinical phenotype and reliable biomarkers need definition. In this study, we have applied a method for Oxford Nanopore sequencing for the unbiased metagenomic characterization of severe asthma. We optimized methods to ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 1.4MB, Terms of use)
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- Publisher copy:
- 10.1128/spectrum.02279-21
Authors
Funding
Bibliographic Details
- Publisher:
- American Society for Microbiology
- Journal:
- Microbiology Spectrum More from this journal
- Volume:
- 10
- Issue:
- 2
- Article number:
- e02279-21
- Publication date:
- 2022-03-24
- Acceptance date:
- 2022-03-02
- DOI:
- EISSN:
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2165-0497
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1247018
- Local pid:
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pubs:1247018
- Deposit date:
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2022-03-24
Terms of use
- Copyright holder:
- Jabeen et al
- Copyright date:
- 2022
- Rights statement:
- © 2022 Jabeen et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
- Licence:
- CC Attribution (CC BY)
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