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Are ethnic inequalities in COVID-19 outcomes mediated by occupation risk? Analyses of a 2-year record linked national cohort study in Scotland

Abstract:
This study investigated the extent to which ethnic inequalities in severe COVID-19 (i.e. hospitalization or deaths) are mediated through occupational risk differences. We used a population-based cohort study linking the 2011 Scottish Census to health records. We included all individuals aged 30-64 years and living in Scotland on 1 March 2020. The study period was from 1 March 2020 to 17 April 2022. Self-reported ethnicity was taken from the Census. We derived occupational risk of SARS-COV-2 infection using the 3-digit Standard Occupational Classification (SOC2010). We estimated hazard ratios (HRs) of total effects and controlled direct effects of ethnicity on severe COVID-19 mediated by occupational risk using marginal structural Cox models and subsequent proportional change. For aggregated ethnic groups, Non-White groups experienced a higher risk of severe COVID-19 (HR 1.6; 95% CI 1.4-1.8) compared to White group (all White ethnic groups) which increased to (1.7; 1.4-2.1) after accounting for occupational risk, representing a 6.0% change. For disaggregated ethnic groups, risks for South Asian (2.0; 1.8-2.3), African, Caribbean, or Black (1.3; 0.9-1.7) and Other ethnic groups (1.1; 0.9-1.3) were higher compared to White Scottish. After accounting for occupational risk, estimated risk of severe COVID-19 remained elevated for South Asian (1.8; 1.2-2.3), African Caribbean or Black (1.4; 0.8-2.1) and Other ethnic group (1.7; 1.1-2.3) representing a reduction of 11.8% and increases of 16.4% and 59.0%, respectively. Our findings suggest that ethnic inequalities in severe COVID-19 were impacted by differences in occupational risk.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/eurpub/ckaf025

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Author
ORCID:
0000-0002-5091-6450
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Role:
Author
ORCID:
0000-0001-8649-6913
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Role:
Author
ORCID:
0000-0001-8616-525X
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Role:
Author
ORCID:
0000-0003-3741-7099


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Funder identifier:
https://ror.org/029chgv08
Grant:
205412/Z/16/Z
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Funder identifier:
https://ror.org/01613vh25
Grant:
Senior Clinical Fellowship SCAF/15/02
SPHSU17
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Funder identifier:
https://ror.org/03x94j517
Grant:
MC_UU_00022/2
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Funder identifier:
https://ror.org/001aqnf71
Grant:
MR/V005146/1
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Funder identifier:
https://ror.org/03n0ht308
Grant:
ES/W000849/1


Publisher:
Oxford University Press
Journal:
European Journal of Public Health More from this journal
Volume:
35
Issue:
2
Pages:
379-385
Publication date:
2025-03-05
DOI:
EISSN:
1464-360X
ISSN:
1101-1262
Pmid:
40044144


Language:
English
Pubs id:
2122109
Local pid:
pubs:2122109
Deposit date:
2025-05-14
ARK identifier:

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