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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Abstract:

Obesity is globaLy prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined aSociations betwEn body maS index and ĝ̂1/42.8 miLion SNPs in up to 123,865 individuals with targeted foLow up of 42 SNPs in up to 125,931 aDitional individuals. We confirmed 14 known obesity susceptibility loci and identified 18 new loci aSociated with body maS index (P < 5-10-8), one of which includes a copy number ...

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Publication status:
Published

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Publisher copy:
10.1038/ng.686

Authors


Speliotes, EK More by this author
Willer, CJ More by this author
Berndt, SI More by this author
Thorleifsson, G More by this author
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Journal:
NATURE GENETICS
Volume:
42
Issue:
11
Pages:
937-U53
Publication date:
2010-11-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:25de0b9c-f8b8-47fc-97a4-bf5a1a731b67
Source identifiers:
93374
Local pid:
pubs:93374
Language:
English

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