Journal article
FcMBL magnetic bead-based MALDI-TOF MS rapidly identifies paediatric blood stream infections from positive blood cultures
- Abstract:
- Fungemia negatively impacts patient outcomes, current diagnostics lack sensitivity to identify emerging rare mycoses, and fungal infections are increasing in prevalence, variety, and resistance. We report a case of Wickerhamomyces anomalus in an immunocompromised neonate in which FcMBL bead-based matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) resulted in species identification roughly 30 hours before standard pathogen identification methods. Deploying FcMBL bead-based MALDI-TOF MS may improve the speed and accuracy of identification, and therefore treatment, of rare pathogens
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.5MB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0276777
- Publication website:
- https://discovery.ucl.ac.uk/10180033/1/Hargrave_1-s2.0-S2211753923000465-main.pdf
Authors
- Publisher:
- Public Library of Science
- Journal:
- PLoS ONE More from this journal
- Volume:
- 17
- Issue:
- 11
- Pages:
- e0276777-e0276777
- Publication date:
- 2022-11-22
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Language:
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English
- Keywords:
- Pubs id:
-
1494100
- Local pid:
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pubs:1494100
- Source identifiers:
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W4309600910
- Deposit date:
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2026-05-11
- ARK identifier:
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Terms of use
- Copyright date:
- 2022
- Licence:
- CC Attribution (CC BY)
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