Journal article icon

Journal article

Bimekizumab treatment in biologic DMARD-naïve patients with active psoriatic arthritis: 52-week efficacy and safety results from the phase 3, randomised, placebo controlled, active reference BE OPTIMAL study

Abstract:

Objectives: Bimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)‑17F in addition to IL‑17A. BKZ treatment has demonstrated superior efficacy versus placebo (PBO) at Week 16 in biologic disease‑modifying antirheumatic drug (DMARD)‑naïve patients with active psoriatic arthritis (PsA). Here, we report longer‑term efficacy and safety to Week 52.

Methods: BE OPTIMAL (NCT03895203) comprised a 16‑week, double‑blind, p...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publication website:
https://ard.bmj.com/content/82/Suppl_1/1133

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0002-4756-663X
Publisher:
BMJ Publishing Group
Journal:
Annals of the Rheumatic Diseases More from this journal
Volume:
82
Issue:
S1
Pages:
1133-1134
Publication date:
2023-05-30
Acceptance date:
2023-07-14
EISSN:
1468-2060
ISSN:
0003-4967
Language:
English
Keywords:
Pubs id:
1492958
Local pid:
pubs:1492958
Deposit date:
2023-07-17

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP