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Effect of CPAP-withdrawal on blood pressure in OSA: data from three randomized-controlled trials

Abstract:

Background

Based on meta-analyses, the blood pressure (BP) lowering effect of continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnea (OSA) is reported to be approximately 2-3mmHg. This figure is derived from heterogeneous trials, often limited by poor CPAP-adherence, and thus possibly underestimating the treatment effect. We analyzed morning BP data from three randomized controlled CPAP withdrawal trials which included only patients with optima...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.chest.2016.07.012

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Clinical Research Priority Program Sleep and Health of the University of Zurich More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Chest Journal website
Volume:
150
Issue:
6
Pages:
1202-1210
Publication date:
2016-07-01
Acceptance date:
2016-07-05
DOI:
ISSN:
1931-3543
Keywords:
Pubs id:
pubs:634556
UUID:
uuid:24a108a9-6bc1-442d-8caf-1b59b5d1416d
Local pid:
pubs:634556
Source identifiers:
634556
Deposit date:
2016-07-19

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