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Site isolated base and acid catalyzed azaspirocyclization cascades.

Abstract:
A one-pot, site isolated base (PS-BEMP) and acid (Si-TsOH) catalyzed cyclization cascade to azaspirocyclic molecules is reported; the reaction is simple to perform, atom efficient (water is the only byproduct) and broad in its scope to a diverse range of azaspirocyclic products.
Publication status:
Published

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Publisher copy:
10.1039/b716568d

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Chemical Communications
Issue:
7
Pages:
832-834
Publication date:
2008-02-01
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
Source identifiers:
34119
Language:
English
Pubs id:
pubs:34119
UUID:
uuid:249c76ab-31e0-4674-a7ea-c1e227a1fe6c
Local pid:
pubs:34119
Deposit date:
2012-12-19

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