- Abstract:
-
Focal lesions and brain atrophy are the most extensively studied aspects of multiple sclerosis (MS), but the image acquisition and analysis techniques used can be further improved, especially those for studying within-patient changes of lesion load and atrophy longitudinally. Improved accuracy and sensitivity will reduce the numbers of patients required to detect a given treatment effect in a trial, and ultimately, will allow reliable characterization of individual patients for personalized t...
Expand abstract - Publisher copy:
- 10.1007/s00415-012-6762-5
-
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- Journal:
- Journal of Neurology
- Volume:
- 260
- Issue:
- 10
- Pages:
- 2458-2471
- Publication date:
- 2013-10-05
- DOI:
- EISSN:
-
1432-1459
- ISSN:
-
0340-5354
- URN:
-
uuid:24947802-14c1-435d-a757-35fae12ab820
- Source identifiers:
-
436290
- Local pid:
- pubs:436290
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Recommendations to improve imaging and analysis of brain lesion load and atrophy in longitudinal studies of multiple sclerosis
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