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Thesis

Multi-scale modelling and simulations into the mechanisms linking neuronal nitric oxide synthase and atrial fibrillation

Abstract:

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Its incidence is projected to rise due to population ageing and increasing prevalence of associated risk factors. AF alters, or remodels, the affected atrial tissue, promoting future occurrences of itself and increasing resistance to treatment. Mechanisms underlying AF initiation and remodelling are not well understood. Recent experimental evidence indicates that decreased levels of the neuronal isoform of Nitric Oxide Synthas...

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Division:
MPLS
Department:
Physics
Sub department:
Atmos Ocean & Planet Physics
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Engineering and Physical Sciences Research Council More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:244d6f3a-00da-4ae8-8d5c-31ebb847806f
Deposit date:
2017-06-22

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