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Identification and functional analysis of an ovarian form of the egg activation factor phospholipase C zeta (PLCζ) in pufferfish.

Abstract:

Recent studies suggest that egg activation in mammals is triggered by a sperm-specific phospholipase C, PLCzeta. In other vertebrate species such as medaka fish, chickens, and quail, PLCzeta is also expressed as a testis-specific mRNA. Functional studies suggest that PLCzeta plays a similar role as a trigger of egg activation in these species. Here, we report the identification of PLCzeta orthologues in pufferfish species Takifugu rubripes (Fugu) and Tetraodon nigroviridis (Tetraodon). Unexpe...

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Publisher copy:
10.1002/mrd.21262

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Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics and Gynaecology
Role:
Author
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Journal:
Molecular reproduction and development
Volume:
78
Issue:
1
Pages:
48-56
Publication date:
2011-01-05
DOI:
EISSN:
1098-2795
ISSN:
1040-452X
URN:
uuid:2446b447-7bf0-4c97-af73-54acc9828157
Source identifiers:
154675
Local pid:
pubs:154675

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