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Journal article

High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection.

Abstract:

BACKGROUND and AIMS: Cellular immune responses are thought to play a key role in the resolution of primary HCV infection. Although it has been consistently shown that CD4+ T-cell responses are maintained in those with spontaneous resolution but lost in those with persistent infection, the role of CD8+ T-cell responses remains controversial. Previous studies have largely focused on limited HLA alleles and predefined CD8+ T-cell epitopes, and, thus, comprehensive studies remain to be performed....

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Publication status:
Published

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Journal:
Gastroenterology More from this journal
Volume:
127
Issue:
3
Pages:
924-936
Publication date:
2004-09-01
DOI:
EISSN:
1528-0012
ISSN:
0016-5085
Language:
English
Keywords:
Pubs id:
pubs:28955
UUID:
uuid:24364c82-d727-4a42-81e7-1025b156be68
Local pid:
pubs:28955
Source identifiers:
28955
Deposit date:
2012-12-19

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