Journal article
Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth
- Abstract:
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Over 20% of cancer patients will suffer metastatic spread to the brain, and prognosis remains poor. Communication between tumour cells and host tissue is essential during metastasis, yet little is known of the processes underlying such interactions in the brain. Here we test the hypothesis that cross-talk between tumour cells and host brain cells, through tumour cell leukocyte function associated protein-1 (LFA-1), is critical in metastasis devel...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 700.1KB)
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(Accepted manuscript, pdf, 1001.9KB)
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- Publisher copy:
- 10.18632/oncotarget.10737
Authors
Funding
Bibliographic Details
- Publisher:
- Impact Journals Publisher's website
- Journal:
- Oncotarget Journal website
- Publication date:
- 2016-06-01
- Acceptance date:
- 2016-06-27
- DOI:
- ISSN:
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1949-2553
Item Description
- Keywords:
- Pubs id:
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pubs:632309
- UUID:
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uuid:243224c1-19da-46f4-a48f-36779d26ad5d
- Local pid:
- pubs:632309
- Source identifiers:
-
632309
- Deposit date:
- 2016-07-07
Terms of use
- Copyright holder:
- Impact Journals
- Copyright date:
- 2016
- Notes:
- Copyright @ 2016 Impact Journals, LLC. All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 License.
- Licence:
- CC Attribution (CC BY)
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