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Role of NOD2 variants in spondylarthritis.

Abstract:

OBJECTIVE: To investigate the role of the gene NOD2 in susceptibility to, and clinical manifestations of, ankylosing spondylitis (AS). METHODS: A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro(268)Ser, Arg(702)Trp, Gly(908)Arg, and Leu(1007)fsinsC) was performed in 229 cases of primary AS with no diagnosed inflammatory bowel disease (IBD), 197 cases of AS associated with IBD (referred to as colitic spondylarthritis; comprising 78 with CD and 11...

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Publication status:
Published

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Publisher copy:
10.1002/art.10329

Authors


Bradbury, L More by this author
van Heel, DA More by this author
McGovern, DP More by this author
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Journal:
Arthritis and rheumatism
Volume:
46
Issue:
6
Pages:
1629-1633
Publication date:
2002-06-05
DOI:
EISSN:
1529-0131
ISSN:
0004-3591
URN:
uuid:24307627-41f5-4a62-9ca2-7f8663568021
Source identifiers:
108548
Local pid:
pubs:108548

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