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Journal article

Virologic response to first-line efavirenz- or nevirapine-based antiretroviral therapy in HIV-infected African children

Abstract:

BACKGROUND: Poorer virologic response to nevirapine- versus efavirenz-based antiretroviral therapy (ART) has been reported in adult systematic reviews and pediatric studies.

METHODS: We compared drug discontinuation and viral load (VL) response in ART-naïve Ugandan/Zimbabwean children ≥3 years of age initiating ART with clinician-chosen nevirapine versus efavirenz in the ARROW trial. Predictors of suppression <80, <400 and <1000 copies/mL at 36, 48 and 144 weeks were identi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1097/INF.0000000000001505

Authors


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Name:
ViiV Healthcare/GlaxoSmithKline
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Name:
Department for International Development
Publisher:
Lippincott, Williams & Wilkins
Journal:
Pediatric Infectious Disease Journal More from this journal
Volume:
36
Issue:
6
Pages:
588-594
Publication date:
2017-06-01
Acceptance date:
2016-08-16
DOI:
EISSN:
1532-0987
ISSN:
0891-3668
Language:
English
Keywords:
Pubs id:
pubs:698559
UUID:
uuid:23c6b072-e680-461a-9a3a-b42cce3ab526
Local pid:
pubs:698559
Source identifiers:
698559
Deposit date:
2017-10-02

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