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Proteomic profiling of the brain of mice with experimental cerebral malaria

Abstract:

Cerebral malaria (CM) is a severe neurological complication of malaria infection in both adults and children. In pursuit of effective treatment of CM, clinical studies, postmortem analysis and animal models have been employed to understand the pathology and identify effective interventions. In this study, a shotgun proteomics analysis was conducted to profile the proteomic signature of the brain tissue of mice with experimental cerebral malaria (ECM) in order to further understand the underly...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/j.jprot.2017.06.002

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Department:
Oxford, MSD, NDM
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Department:
Oxford, MSD, NDM, Target Discovery Institute
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Publisher:
Elsevier Publisher's website
Journal:
Journal of Proteomics Journal website
Volume:
180
Pages:
61-69
Publication date:
2017-06-05
Acceptance date:
2017-06-01
DOI:
EISSN:
1876-7737
ISSN:
1874-3919
Pubs id:
pubs:700545
URN:
uri:23ac3b8a-2f5d-4c79-9c62-0500511165b6
UUID:
uuid:23ac3b8a-2f5d-4c79-9c62-0500511165b6
Local pid:
pubs:700545

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