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Journal article : Review

Ischemia and reperfusion injury in kidney transplantation: Relevant mechanisms in injury and repair

Abstract:

Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation. Long term, it is associated with acute rejection and chronic graft dysfunction due to interstitial fibrosis and tubular atrophy. Recently, more insight has been gained in the underlying molecular pathways and signalling cascades involved, which opens the door to new therap...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3390/jcm9010253

Authors


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Role:
Author
ORCID:
0000-0001-9874-2632
More by this author
Role:
Author
ORCID:
0000-0003-2543-3251
Publisher:
MDPI
Journal:
Journal of Clinical Medicine More from this journal
Volume:
9
Issue:
1
Article number:
253
Publication date:
2020-01-17
Acceptance date:
2020-01-13
DOI:
EISSN:
2077-0383
Pmid:
31963521
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1083873
Local pid:
pubs:1083873
Deposit date:
2020-10-05

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