Influence of dose and duration of smoking on lung cancer rates.

Journal article

Lung cancer risks depend far more strongly on the duration than on the daily dose-rate of cigarette smoking. For example, a three-fold increase in the daily dose-rate may produce only about a three-fold increase in effect, while a three-fold increase in duration might produce about a 100-fold increase in effect. Hence, a few decades after cigarette smoking becomes widespread, national lung cancer rates may remain very misleadingly low, even though they will eventually become extremely high.

Authors: Peto, R

• Journal: IARC scientific publications
• Issue: 74
• Pages: 23-33
• Publication date: 1986-01-01
• ISSN: 0300-5038
• Language: English
• Keywords: Humans; Age Factors; Risk; Dose-Response Relationship, Drug; Lung Neoplasms; Smoking; Time Factors