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Systematic review of purine analog treatment for chronic lymphocytic leukemia: lessons for future trials.

Abstract:

A systematic review of purine analogs revealed heterogeneity between trials in treatment effects on response and progression free survival, but not survival, perhaps partly due to variations in analytical methods. In addition, combination treatments required evaluation. Therefore, individual patient data were sought for all randomized trials in untreated chronic lymphocytic leukemia which involved a purine analog, but which did not include antibody therapies. Sixteen trials were found, addres...

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Publication status:
Published

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Authors


CLL Trialists’ Collaborative Group More by this author
Journal:
Haematologica
Volume:
97
Issue:
3
Pages:
428-436
Publication date:
2012-03-05
DOI:
EISSN:
1592-8721
ISSN:
0390-6078
URN:
uuid:23720532-ca11-47fa-8708-486f3eccec59
Source identifiers:
216116
Local pid:
pubs:216116

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