- Abstract:
-
A systematic review of purine analogs revealed heterogeneity between trials in treatment effects on response and progression free survival, but not survival, perhaps partly due to variations in analytical methods. In addition, combination treatments required evaluation. Therefore, individual patient data were sought for all randomized trials in untreated chronic lymphocytic leukemia which involved a purine analog, but which did not include antibody therapies. Sixteen trials were found, addres...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.3324/haematol.2011.053512
-
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- Journal:
- Haematologica
- Volume:
- 97
- Issue:
- 3
- Pages:
- 428-436
- Publication date:
- 2012-03-05
- DOI:
- EISSN:
-
1592-8721
- ISSN:
-
0390-6078
- URN:
-
uuid:23720532-ca11-47fa-8708-486f3eccec59
- Source identifiers:
-
216116
- Local pid:
- pubs:216116
- Copyright date:
- 2012
Journal article
Systematic review of purine analog treatment for chronic lymphocytic leukemia: lessons for future trials.
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