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Patterns of RNA editing in Newcastle disease virus infections

Abstract:

The expression of accessory non-structural proteins V and W in Newcastle disease virus (NDV) infections depends on RNA editing. These proteins are derived from frameshifts of the sequence coding for the P protein via co-transcriptional insertion of one or two guanines in the mRNA. However, a larger number of guanines can be inserted with lower frequencies. We analysed data from deep RNA sequencing of samples from in vitro and in vivo NDV infections to uncover the patterns of mRNA editing in N...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/v12111249

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Biotechnology and Biological Sciences Research Council More from this funder
Publisher:
MDPI Publisher's website
Journal:
Viruses Journal website
Volume:
12
Issue:
11
Article number:
1249
Publication date:
2020-11-02
Acceptance date:
2020-10-30
DOI:
EISSN:
1999-4915
Pmid:
33147786

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