Journal article icon

Journal article

Evidence that the anxiolytic-like effects of chlordiazepoxide on the elevated plus maze are confounded by increases in locomotor activity.

Abstract:

In exploratory animal models of anxiety, such as the elevated plus maze, the anxiogenic- and anxiolytic-like effects of drugs may be confounded by changes in locomotor activity. In the present experiments, the sensitivity of several measures of anxiety and locomotor activity in the elevated plus maze were assessed. Both chlordiazepoxide hydrochloride (CDP, 7.5 mg/kg) and d-amphetamine sulphate (AMP, 0.75, 1.5 mg/kg) increased the percent time on the open arms and doses of 7.5 mg/kg and 1.5 mg...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/bf02245961

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Journal:
Psychopharmacology
Volume:
118
Issue:
3
Pages:
316-323
Publication date:
1995-04-01
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
Source identifiers:
22316
Language:
English
Keywords:
Pubs id:
pubs:22316
UUID:
uuid:231deefc-4125-47a7-b7f7-23ec28a89adf
Local pid:
pubs:22316
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP