Journal article

Immune responses against a liver-stage malaria antigen induced by simian adenoviral vector AdCh63 and MVA prime-boost immunisation in non-human primates

Abstract:: Malaria is a major health problem as nearly half of the human population is exposed to this parasite causing around 600 million clinical cases annually. Prime-boost regimes using simian adenoviral vectors and MVA expressing the clinically relevant Plasmodium falciparum ME.TRAP antigen have shown outstanding protective efficacy in mouse models. We now extend those observations to macaque monkeys. Immunisation with AdCh63 elicited a median response of 869 IFN-γ SFC/million PBMCs to ME.TRAP and ...
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APA Style

Capone, S., Reyes-Sandoval, A., Naddeo, M., Siani, L., Ammendola, V., Rollier, C., Nicosia, A., Colloca, S., Cortese, R., Folgori, A., & Hill, A. (2010). Immune responses against a liver-stage malaria antigen induced by simian adenoviral vector AdCh63 and MVA prime-boost immunisation in non-human primates. Vaccine, 29(2), 256–265.

MLA Style

Capone, S., et al. “Immune Responses against a Liver-Stage Malaria Antigen Induced by Simian Adenoviral Vector AdCh63 and MVA Prime-Boost Immunisation in Non-Human Primates.” Vaccine, vol. 29, no. 2, 2010, pp. 256–65.

Chicago Style

Capone, S, A Reyes-Sandoval, M Naddeo, L Siani, V Ammendola, C Rollier, A Nicosia, et al. 2010. “Immune Responses against a Liver-Stage Malaria Antigen Induced by Simian Adenoviral Vector AdCh63 and MVA Prime-Boost Immunisation in Non-Human Primates.” Vaccine 29 (2): 256–65.
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Publisher copy:: 10.1016/j.vaccine.2010.10.041

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+ Capone, S More by this author

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+ Reyes-Sandoval, A More by this author

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+ Naddeo, M More by this author

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+ Siani, L More by this author

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+ Ammendola, V More by this author

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Bibliographic Details

Journal:: Vaccine More from this journal
Volume:: 29
Issue:: 2
Pages:: 256-265
Publication date:: 2010-12-16
DOI:: 10.1016/j.vaccine.2010.10.041
ISSN:: 0264-410X

Item Description

Language:: English
Keywords:: Malaria vaccine

Macaque

MVA

Simian adenovirus
Pubs id:: pubs:107178
UUID:: uuid:228d1ebb-923b-406d-88d7-6668176037a0
Local pid:: pubs:107178
Source identifiers:: 107178
Deposit date:: 2012-12-19

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Copyright date:: 2010

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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