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Tissue macrophage heterogeneity: Issues and prospects

Abstract:

The vast majority of macrophages in the body are present in tissues outside the circulation, yet their remarkable phenotypic heterogeneity within different anatomical compartments in the steady state and disease remains essentially unexplored. The development of immunocytochemical and fluorescent histological methods has revealed the presence and morphological diversity of macrophages within tissues, especially in the mouse, but functional specialisation in situ is difficult to establish and ...

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Publisher copy:
10.1007/s00281-013-0386-4

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
Journal:
Seminars in Immunopathology More from this journal
Volume:
35
Issue:
5
Pages:
533-540
Publication date:
2013-09-01
DOI:
EISSN:
1863-2300
ISSN:
1863-2297
Language:
English
Keywords:
Pubs id:
pubs:426358
UUID:
uuid:21ff3f08-43f2-4423-bff5-a6000dac18d2
Local pid:
pubs:426358
Source identifiers:
426358
Deposit date:
2013-11-17

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