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Journal article

Creatine transporter activity and content in the rat heart supplemented by and depleted of creatine.

Abstract:

The intracellular creatine concentration is an important bioenergetic parameter in cardiac muscle. Although creatine uptake is known to be via a NaCl-dependent creatine transporter (CrT), its localization and regulation are poorly understood. We investigated CrT kinetics in isolated perfused hearts and, by using cardiomyocytes, measured CrT content at the plasma membrane or in total lysates. Rats were fed control diet or diet supplemented with creatine or the creatine analog beta-guanidinopro...

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Publication status:
Published

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Publisher copy:
10.1152/ajpendo.00259.2002

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
American journal of physiology. Endocrinology and metabolism More from this journal
Volume:
284
Issue:
2
Pages:
E399-E406
Publication date:
2003-02-01
DOI:
EISSN:
1522-1555
ISSN:
0193-1849
Language:
English
Keywords:
Pubs id:
pubs:162324
UUID:
uuid:21cbcdef-13ed-41e0-8b37-b5a3dd729eb2
Local pid:
pubs:162324
Source identifiers:
162324
Deposit date:
2012-12-19

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