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An optimized set of human telomere clones for studying telomere integrity and architecture

Abstract:

Telomere-specific clones are a valuable resource for the characterization of chromosomal rearrangements. We previously reported a first-generation set of human telomere probes consisting of 34 genomic clones, which were a known distance from the end of the chromosome (~300 kb), and 7 clones corresponding to the most distal markers on the integrated genetic/physical map (1p, 5p, 6p, 9p, 12p, 15q, and 20q). Subsequently, this resource has been optimized and completed: the size of the genomic cl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
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Institution:
University of Chicago
Department:
Department of Human Genetics
Role:
Author
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Institution:
University of Chicago
Department:
Department of Human Genetics
Role:
Author
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Institution:
University of Chicago
Department:
Department of Human Genetics
Role:
Author
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Institution:
"Gene-Care Medical Genetics Center and George Washington University, Washington, DC"
Role:
Author

Contributors

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Name:
"March of Dimes", "National Institutes of Health", "Vysis Inc."
Funding agency for:
Ledbetter, D
Grant:
"6-FY99-641", "1-R01-HD36715-01"
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Name:
National Research Service Award
Funding agency for:
Lese, C
Grant:
1 F32 HG00174-01
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Name:
"Wellcome Trust", "Cytocell Ltd."
Funding agency for:
Flint, J
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Name:
Wellcome Trust
Funding agency for:
Knight, S
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Name:
National Human Genome Research Institute
Publisher:
University of Chicago Press
Journal:
American Journal of Human Genetics More from this journal
Volume:
67
Issue:
2
Pages:
320-332
Publication date:
2000-08-01
ISSN:
0002-9297
Language:
English
Keywords:
Subjects:
UUID:
uuid:21bd4137-3e30-450d-95b7-8459a40c2485
Local pid:
ora:1032
Deposit date:
2008-03-14

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