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Considering genomic and immunological correlates of protection for a dengue intervention

Abstract:

Over three billion are at risk of dengue infection with more than 100 million a year presenting with symptoms that can lead to deadly haemorrhagic disease. There are however no treatments available and the only licensed vaccine shows limited efficacy and is able to enhance the disease in some cases. These failures have mainly been due to the complex pathology and lack of understanding of the correlates of protection for dengue virus (DENV) infection. With increasing data suggesting both a pro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3390/vaccines7040203

Authors


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Role:
Author
ORCID:
0000-0003-3624-7008
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
CCMP
Role:
Author
ORCID:
0000-0002-2648-1696
Publisher:
MDPI
Journal:
Vaccines More from this journal
Volume:
7
Issue:
4
Article number:
203
Publication date:
2019-12-03
Acceptance date:
2019-11-27
DOI:
EISSN:
2076-393X
ISSN:
2076-393X
Pmid:
31816907
Language:
English
Keywords:
Pubs id:
pubs:1078239
UUID:
uuid:21bcad64-922f-4eca-ba34-8cea561c61f7
Local pid:
pubs:1078239
Source identifiers:
1078239
Deposit date:
2019-12-23

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