Thesis
The effects of laser-assisted zona pellucida manipulations on embryo competency and the mechanisms underlying embryo hatching in a mouse model
- Abstract:
-
Mammalian embryo hatching from the zona pellucida (ZP) is a prerequisite to undergo subsequent implantation, but little is known about the involved molecules and regulatory mechanisms underlying the hatching process. Hatching failure can lead to implantation failure. Clinical laboratories have developed the non-contact infra-red diode laser to manipulate ZP for various purpose, such as assist embryo hatching and facilitate embryo biopsy procedure. Previous studies attempted to investigate the...
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Authors
Contributors
+ Jones, C
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Women's & Reproductive Health
- Sub department:
- Women's & Reproductive Health
- Role:
- Contributor
+ Coward, K
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Women's & Reproductive Health
- Sub department:
- Women's & Reproductive Health
- Role:
- Supervisor
- ORCID:
- 0000-0003-3577-4041
+ Granne, I
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Women's & Reproductive Health
- Sub department:
- Women's & Reproductive Health
- Role:
- Supervisor
+ Child, T
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Women's & Reproductive Health
- Sub department:
- Women's & Reproductive Health
- Role:
- Examiner
+ Griffin, D
- Institution:
- University of Kent
- Role:
- Examiner
+ China Scholarship Council
More from this funder
- Funder identifier:
- http://dx.doi.org/10.13039/501100004543
- Funding agency for:
- Liu, Y
- Grant:
- 201808060120
- Programme:
- Chinese government scholarship
+ Rosetrees Trust
More from this funder
- Funder identifier:
- http://dx.doi.org/10.13039/501100000833
- Funding agency for:
- Jones, C
- Coward, K
- Grant:
- CM541
- Programme:
- Refining infra-red laser applications to facilitate embryo implantation in assisted reproductive technology
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
-
- Subjects:
- Deposit date:
-
2021-10-28
Terms of use
- Copyright holder:
- Liu, Y
- Copyright date:
- 2021
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