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Effects of long-term opioid analgesics on cognitive performance and plasma cytokine concentrations in patients with chronic low back pain: a cross-sectional pilot study

Abstract:

Introduction: Cognitive performance and inflammation are altered in people with chronic low back pain (CLBP). Yet, the magnitude of these changes has been unclear because of the potential influence of opioid analgesics. Objectives: This cross-sectional pilot study aimed to explore whether patients with CLBP receiving long-term opioid analgesics differed from patients not taking opioids on measures of cognitive performance and plasma cytokine concentrations. Methods: Patients with CLBP who w...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1097/PR9.0000000000000669

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care Health Sciences
Oxford college:
Kellogg College
ORCID:
0000-0003-0244-5620
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Publisher:
Lippincott, Williams and Wilkins Publisher's website
Journal:
PAIN Reports Journal website
Volume:
3
Issue:
4
Pages:
Article: e669
Publication date:
2018-07-16
Acceptance date:
2018-06-08
DOI:
EISSN:
2471-2531
Pubs id:
pubs:891824
URN:
uri:2107d369-ab94-479a-ad4e-0bc130407384
UUID:
uuid:2107d369-ab94-479a-ad4e-0bc130407384
Local pid:
pubs:891824

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