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Journal article

The immunological synapse.

Abstract:

The adaptive immune response is initiated by the interaction of T cell antigen receptors with major histocompatibility complex molecule-peptide complexes in the nanometer scale gap between a T cell and an antigen-presenting cell, referred to as an immunological synapse. In this review we focus on the concept of immunological synapse formation as it relates to membrane structure, T cell polarity, signaling pathways, and the antigen-presenting cell. Membrane domains provide an organizational pr...

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Journal:
Annual review of immunology
Volume:
19
Pages:
375-396
Publication date:
2001-01-01
DOI:
EISSN:
1545-3278
ISSN:
0732-0582
URN:
uuid:2101d7aa-d2c8-439c-9749-33101bd97689
Source identifiers:
482664
Local pid:
pubs:482664

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