- Abstract:
-
The adaptive immune response is initiated by the interaction of T cell antigen receptors with major histocompatibility complex molecule-peptide complexes in the nanometer scale gap between a T cell and an antigen-presenting cell, referred to as an immunological synapse. In this review we focus on the concept of immunological synapse formation as it relates to membrane structure, T cell polarity, signaling pathways, and the antigen-presenting cell. Membrane domains provide an organizational pr...
Expand abstract - Publisher copy:
- 10.1146/annurev.immunol.19.1.375
-
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- Journal:
- Annual review of immunology
- Volume:
- 19
- Pages:
- 375-396
- Publication date:
- 2001-01-01
- DOI:
- EISSN:
-
1545-3278
- ISSN:
-
0732-0582
- URN:
-
uuid:2101d7aa-d2c8-439c-9749-33101bd97689
- Source identifiers:
-
482664
- Local pid:
- pubs:482664
- Language:
- English
- Keywords:
- Copyright date:
- 2001
Journal article
The immunological synapse.
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