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Thesis

Characterisation of the histone acetyltransferase KAT7 as a novel target for radiosensitisation

Abstract:

Radiotherapy is one of the pillars of modern cancer therapy. However, side effects associated with normal tissue toxicity limit the effectiveness of this treatment. It is therefore desirable to develop tumour-specific radiosensitising agents, which can increase tumour cell kill without increasing the radiosensitivity of the surrounding normal tissue.

This project aimed at validating the radiosensitising potential of depletion of the histone acetyltransferase KAT7, and elucidating th...

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Authors


Martin-Immanuel Bittner More by this author

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Role:
Supervisor
Role:
Supervisor
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Project
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Funding agency for:
Project
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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