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Unlearning scanner bias for MRI harmonisation in medical image segmentation

Abstract:
The combination of datasets is vital for providing increased statistical power, and is especially important for neurological conditions where limited data is available. However, our ability to combine datasets is limited by the addition of variance caused by factors such as differences in acquisition protocol and hardware. We aim to create scanner-invariant features using an iterative training scheme based on domain adaptation techniques, whilst simultaneously completing the desired segmentation task. We demonstrate the technique using an encoder-decoder architecture similar to the U-Net but expect that the proposed training scheme would be applicable to any feedforward network and task. We show that the network can be used to harmonise two datasets and also show that the network is applicable in the common scenario of limited available training data, meaning that the network should be applicable for real-world segmentation problems.
Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Oxford college:
Worcester College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Sub department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0001-6043-0166


Publisher:
Springer
Host title:
Communications in Computer and Information Science
Series:
Communications in Computer and Information Science
Series number:
1248
Publication date:
2020-07-15
Acceptance date:
2020-05-04
Event title:
MIUA 2020: Medical Image Understanding and Analysis
Event series:
Annual Conference on Medical Image Understanding and Analysis
Event location:
Online
Event website:
https://miua2020.com/
Event start date:
2020-07-15
Event end date:
2020-10-17
DOI:
EISBN:
978-3-030-52791-4
ISBN:
978-3-030-52790-7


Language:
English
Keywords:
Subtype:
Presentation
Pubs id:
1123231
Local pid:
pubs:1123231
Deposit date:
2020-10-22

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