Journal article icon

Journal article

The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells.

Abstract:

The ch-TOG/XMAP215 family of proteins bind directly to microtubules and appear to play an essential role in stabilizing spindle microtubules. These proteins stabilize microtubules mainly by influencing microtubule plus-end dynamics, yet, in vivo, they are all strongly concentrated at spindle poles, where the minus ends of the microtubules are concentrated. In Drosophila embryos, the centrosomal protein D-TACC is required to efficiently recruit ch-TOG/Msps to centrosomes. In humans, ch-TOG and...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1101/gad.245603
Journal:
Genes and development More from this journal
Volume:
17
Issue:
3
Pages:
336-341
Publication date:
2003-02-01
DOI:
EISSN:
1549-5477
ISSN:
0890-9369
Language:
English
Keywords:
Pubs id:
pubs:223377
UUID:
uuid:1f94efcc-0ea5-40b4-a4e3-a0a8469ac692
Local pid:
pubs:223377
Source identifiers:
223377
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP