Thesis
Studies on collagen post-translational modifications
- Abstract:
-
The collagen proteins are the principal component of the extracellular matrix and are the most abundant protein family in humans. Therefore, collagens form the major protein component of bone, tendon and cartilage. During collagen biosynthesis, proline and lysine residues are enzymatically converted to (2S,4R)-hydroxyproline, (2S,3S)-hydroxyproline and (2S,5R)-hydroxylysine by the collagen prolyl-4-hydroxylases (C-P4Hs), prolyl-3-hydroxylases (P3Hs) and proc...
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Authors
Contributors
+ Schofield, C
- Department:
- University of Oxford
- Role:
- Supervisor
+ Carr, A
- Department:
- University of Oxford
- Role:
- Supervisor
+ Claridge, T
- Department:
- University of Oxford
- Role:
- Examiner
+ Jung, M
- Department:
- Albert-Ludwigs-Universität Freiburg
- Role:
- Examiner
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- UUID:
-
uuid:1f7da2dd-9626-4aba-87ed-ee70736e9bed
- Deposit date:
-
2018-05-04
Terms of use
- Copyright holder:
- Langley, G
- Copyright date:
- 2017
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