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Thesis

Studies on collagen post-translational modifications

Abstract:

The collagen proteins are the principal component of the extracellular matrix and are the most abundant protein family in humans. Therefore, collagens form the major protein component of bone, tendon and cartilage. During collagen biosynthesis, proline and lysine residues are enzymatically converted to (2S,4R)-hydroxyproline, (2S,3S)-hydroxyproline and (2S,5R)-hydroxylysine by the collagen prolyl-4-hydroxylases (C-P4Hs), prolyl-3-hydroxylases (P3Hs) and proc...

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Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Department:
University of Oxford
Role:
Author

Contributors

Department:
University of Oxford
Role:
Supervisor
Department:
University of Oxford
Role:
Supervisor
Department:
University of Oxford
Role:
Examiner
Department:
Albert-Ludwigs-Universität Freiburg
Role:
Examiner


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


UUID:
uuid:1f7da2dd-9626-4aba-87ed-ee70736e9bed
Deposit date:
2018-05-04

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