Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy

Conference item

Colorectal cancer (CRC) is acommon cause of cancerrelated deaths (12.2% overall mortality, GLOBOCAN 2012 v1.0). Approximately half of CRC patients develop or present with metastasis (mCRC) to the liver. Selective internal radiation therapy (SIRT) involves injection of yttrium-90 (90Y) radiolabelledmicrospheres into the arterial blood supply of tumours in the liver. Radioactivity prescription for 90YSIRTis currently based on a body surface area (BSA) formula. The purpose of this study was to conduct a lesion-by-lesion analysis to establish a dose-response relationship.

Authors: Abbott, E; Falzone, N; Winter, H; Greenhalgh, T; Kartsonaki, C

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Elsevier
• Host title: ASTRO's 59th Annual Meeting
• Journal: ASTRO's 59th Annual Meeting
• Publication date: 2017-09-23
• DOI: 10.1016/j.ijrobp.2017.06.915
• EISSN: 1879-355X
• ISSN: 0360-3016